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U.S. regulators said  they would review whether to take action over the popular cholesterol drug Vytorin after a study showed it was no better than a generic in preventing the build-up of fatty plaque.

The makers of popular cholesterol drugs Vytorin and Zetia are being sued in at least four states over allegations that Merck & Co. and Schering-Plough Corp. misled consumers into thinking the drugs were more effective than generic ones.

Patients with a predisposition to high cholesterol fared no better when taking their combination cholesterol drug Vytorin than with a high dose of the generic form of Zocor, a study shows.